ANTIBACTERIAL PROPERTIES OF Ginkgo biloba EXTRACT ON MICROORGANISM STRAINS IN VITRO EXPERIMENTS
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Abstract
The pressing issue of antibiotic resistance demands immediate attention. Scientists are exploring alternative remedies, including plant-based solutions, to prevent infectious diseases. This study investigates the antibacterial properties of Ginkgo biloba extract in vitro. Ginkgo biloba contains specific compounds - terpenlactones (terpenic lactones: ginkgolides, bilobalides) and flavonoglycosides (flavonoids: quercetin, kaempferol, isorhamnetin, proanthocyanidins), which regulate metabolic processes, normalize cellular metabolism, and improve blood rheology and microcirculation. The research aims to examine the antimicrobial effects of ethanolic Ginkgo biloba extract on various strains of microorganisms in experiments conducted in vitro. The antibacterial activity of the plant extract was evaluated using the disc diffusion method against reference strains of Enterobacteriaceae, Pseudomonadaceae, Staphylococcaceae, Bacillaceae, Listeriaceae, Campylobacter jejuni, Corynebacterium xerosis, and Candida albicans. The experiments demonstrated significant antibacterial efficacy against a range of microorganisms, suggesting the potential of Ginkgo biloba extracts in combating polyresistant strains. This research received support from the Ministry of Education and Science of Ukraine (grant 0117U006533).
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